Abstraction Health

Spermidine

Polyamine
🟡Moderate Evidence 12 expert mentions 20 studies
F·31/100·Insufficient
Research Depth25/25
Study Quality0/25
Expert Consensus6/25
Claim Support0/25

A naturally occurring polyamine found in wheat germ, soybeans, and aged cheese. Studied for autophagy induction, longevity, cardiovascular health, and cognitive function.

Evidence comparisons not yet run for these claims.

Expert Consensus

Pending review
1/5
Experts mention
1
Recommend
0
Flag caution
DS
David Sinclair Recommends
Pending review12 claims1.2g

Expert Mentions

All 12 mentions
DS
David Sinclair
Harvard Medical School
Evidence-backed claim

The one that stands out for me is the one by Schwartz et al 2018. They were giving people 1.2 g per day over 3 months and there was significant enhancement of memory.

Extracted claim

A study by Schwartz et al. 2018 gave people 1.2 g of spermidine per day over 3 months and found significant enhancement of memory.

1.2 gper day📍 administered over 3 months in a human study on memory
Not yet assessedHigh confidence
DS
David Sinclair
Harvard Medical School
Evidence-backed claim

There've been a number of human studies on spermidine uh particularly revolving around enhancing memory and dealing with memory loss in older Americans. That's true. We don't know a lot about aging itself but cognition has greatly improved in a number of studies.

Extracted claim

Human studies on spermidine have shown enhancement of memory and improvement in memory loss in older individuals.

Not yet assessedHigh confidence

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