Abstraction Health

CJC-1295

Peptide
🟠Weak Evidence 9 expert mentions 1 studies
F·21/100·Insufficient
Research Depth1/25
Study Quality13/25
Expert Consensus7/25
Claim Support0/25

A synthetic peptide that stimulates growth hormone release by binding to GHRH receptors. Used for muscle growth, fat loss, and recovery. Often combined with ipamorelin.

Evidence comparisons not yet run for these claims.

Expert Consensus

Mixed opinionsPending review
2/5
Experts mention
1
Recommend
1
Flag caution
MH
Mark Hyman Recommends Caution
Pending review8 claimsinjection
DS
Pending review1 claim

Evidence Summary

PubMed / NCBI·May 2026
All 1 studies
1
Studies
0
RCTs
1
Reviews

Significant limitations exist across the board. There are no clinical trials in this dataset evaluating CJC-1295's effects on body composition, growth hormone levels, recovery, or any other outcome. The sole study provides no quantitative data, no control group, and no verified health outcomes — only anecdotal, self-reported accounts from an unspecified online population. The long-term safety profile of CJC-1295, potential hormonal side effects, optimal dosing, and interactions with other substances remain entirely uncharacterized by the research reviewed here. Anyone considering this supplement should be aware that the evidence base, at least as represented here, does not support evidence-based decision-making.

Read full evidence summary →

Top studies

Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions.

Substance use & misuse · 2016 · Van Hout MC et al.
Review🟡
Key finding

Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions.

PMID: 26771670DOI: 10.3109/10826084.2015.1082595
View on PubMed

Expert Mentions

All 9 mentions
MH
Mark Hyman
Cleveland Clinic Center for Functional Medicine
Caution / warning

it's worse if you drink alcohol if you have wine so I had wine and then I injected and I felt like I was on fire

Extracted claim

The burning sensation from CJC-1295 is worse if you have consumed alcohol beforehand.

injection📍 Combined with alcohol consumption
Not yet assessedHigh confidence
MH
Mark Hyman
Cleveland Clinic Center for Functional Medicine
Caution / warning

it's worse if you drink alcohol if you have wine so I had wine and then I injected and I felt like I was on fire

Extracted claim

The burning sensation from CJC-1295 is worse if you have consumed alcohol beforehand.

injection📍 Combined with alcohol consumption
Not yet assessedHigh confidence

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Key findings

  • ·Only one study was identified, and it was a netnography (qualitative analysis of online discussions), not a clinical trial.
  • ·The study focused exclusively on female use patterns and self-reported experiences with CJC-1295 in online communities.
  • ·No quantitative outcomes, population sizes, or specific findings were available from the study.

Evidence gaps

  • ·There are no clinical trials in the reviewed literature measuring the actual physiological effects of CJC-1295 in humans, including impacts on growth hormone levels, body composition, or recovery.
  • ·The safety profile of CJC-1295 — including hormonal side effects, long-term risks, and drug interactions — is completely unaddressed by the available research.
  • ·Effective dosing, timing, and population-specific responses (e.g., by sex, age, or health status) have not been studied in the provided evidence base.