Mood

A fat-soluble vitamin critical for bone health, immune function, and mood regulation. Deficiency is widespread.

Rich in EPA and DHA omega-3 fatty acids. Studied for cardiovascular, brain, and anti-inflammatory benefits.

An essential mineral involved in over 300 enzymatic reactions. Widely studied for sleep, anxiety, and metabolic health.

Inositol is a naturally occurring sugar alcohol that functions as a critical second messenger in cellular signaling, particularly through the IP3 pathway and insulin signal transduction. It is found in a range of foods and is produced endogenously. The most studied form, myo-inositol, has its strongest evidence base in polycystic ovary syndrome (PCOS), where it appears to improve insulin sensitivity and hormonal regulation. High-dose myo-inositol (12-18g/day) has been studied for anxiety and panic disorder with preliminary positive findings. Lower-dose use for sleep (approximately 900mg) is discussed in wellness contexts but has limited direct trial evidence at that specific dose.